Basic Information
ID: ALA4233627
Type: Binding
Description: Inhibition of recombinant human topoisomerase-2alpha expressed in Saccharomyces cerevisiae assessed as stabilization of DNA-enzyme cleavage complex at 25 uM incubated for 10 mins followed by incubation in drug-free buffer by agarose gel electrophoresis method
Format: BAO_0000019
Organism: Homo sapiens
Target: DNA topoisomerase II alpha(ALA1806)
Document: ALA4229437
Inhibition of recombinant human topoisomerase-2alpha expressed in Saccharomyces cerevisiae assessed as stabilization of DNA-enzyme cleavage complex at 25 uM incubated for 10 mins followed by incubation in drug-free buffer by agarose gel electrophoresis method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4233627
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 655.79 | 1.78 | 1.78 |
| 613.71 | 0.74 | 0.74 |
| 641.77 | 1.52 | 1.52 |
| 627.74 | 1.13 | 1.13 |
| 584.67 | 1.54 | 1.54 |
| 643.73 | 2.37 | 2.37 |