Basic Information
ID: ALA4233634
Type: Binding
Description: Inhibition of recombinant human topoisomerase-2beta expressed in Saccharomyces cerevisiae assessed as increase in total DNA cleavage at 25 uM using supercoiled pBR322 DNA as substrate incubated for 6 mins measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis method relative to etoposide
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4233634
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 655.79 | 1.78 | 1.78 |
| 613.71 | 0.74 | 0.74 |
| 641.77 | 1.52 | 1.52 |
| 627.74 | 1.13 | 1.13 |
| 584.67 | 1.54 | 1.54 |
| 643.73 | 2.37 | 2.37 |