Basic Information
ID: ALA4234012
Type: Binding
Description: Antagonist activity at full length human FXR expressed in HeLa cells co-expressing BSEP-pGL3/pSG5-hRXR assessed as inhibition of GW4064-induced receptor activation after 24 hrs by luciferase reporter gene assay
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA4234012
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 319.36 | 3.65 | 3.65 |
| 325.41 | 4.25 | 4.25 |
| 400.26 | 5.54 | 5.54 |
| 325.41 | 4.42 | 4.42 |
| 361.40 | 4.24 | 4.24 |
| 311.38 | 3.86 | 3.86 |
| 311.38 | 3.86 | 3.86 |
| 331.37 | 4.23 | 4.23 |
| 401.51 | 5.46 | 5.46 |
| 331.37 | 4.23 | 4.23 |
| 341.41 | 3.87 | 3.87 |
| 361.40 | 4.24 | 4.24 |
| 339.44 | 4.64 | 4.64 |
| 305.33 | 3.72 | 3.72 |
| 341.41 | 3.87 | 3.87 |
| 327.38 | 3.57 | 3.57 |
| 341.41 | 3.87 | 3.87 |
| 325.41 | 3.89 | 3.89 |
| 325.41 | 4.17 | 4.17 |
| 305.33 | 3.72 | 3.72 |
| 341.41 | 3.87 | 3.87 |
| 311.38 | 3.86 | 3.86 |
| 311.38 | 3.86 | 3.86 |
| 325.41 | 4.17 | 4.17 |