Basic Information
ID: ALA4234939
Type: Binding
Description: Inhibition of C-terminal His-tagged recombinant human ACC1 (1 to 2383 residues) expressed in Baculovirus infected Sf9 insect cells using acetyl CoA as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by ADP-Glo assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Acetyl-CoA carboxylase 1(ALA3351)
Document: ALA4229482
Inhibition of C-terminal His-tagged recombinant human ACC1 (1 to 2383 residues) expressed in Baculovirus infected Sf9 insect cells using acetyl CoA as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by ADP-Glo assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4234939
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.50 | 3.46 | 3.46 |
| 442.44 | 4.24 | 4.24 |
| 495.55 | 5.72 | 5.72 |
| 560.62 | 7.03 | 7.03 |
| 441.45 | 4.85 | 4.85 |
| 413.48 | 3.40 | 3.40 |
| 441.45 | 4.85 | 4.85 |
| 453.46 | 4.91 | 4.91 |
| 453.46 | 4.91 | 4.91 |
| 508.50 | 5.50 | 5.50 |
| 431.47 | 3.54 | 3.54 |
| 456.47 | 4.55 | 4.55 |
| 446.51 | 3.32 | 3.32 |
| 427.51 | 3.71 | 3.71 |
| 518.54 | 5.91 | 5.91 |
| 481.52 | 5.33 | 5.33 |
| 453.46 | 4.91 | 4.91 |
| 432.48 | 3.23 | 3.23 |
| 456.47 | 4.55 | 4.55 |
| 519.53 | 5.30 | 5.30 |
| 498.55 | 5.50 | 5.50 |