Basic Information
ID: ALA4235562
Type: Binding
Description: Antagonist activity at FLAG-tagged human TLR2/TLR1 expressed in HEK293 cells co-expressing pGL3-Elam.luc assessed as inhibition of Pam3CSK4-stimulated NF-kappaB activation at 50 uM preincubated for 1 hr followed by Pam3CSK4 stimulation for 5 hrs by luciferase reporter gene assay relative to control
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4235562
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1354.55 | ||
| 1483.74 | ||
| 1100.33 | ||
| 966.10 | -1.67 | -1.67 |
| 1161.43 | ||
| 1214.48 | ||
| 1026.13 | ||
| 1255.49 | ||
| 1135.35 |