Assay Report Card

Basic Information

ID: ALA4235564

Type: Binding

Description: Antagonist activity at FLAG-tagged human TLR2/TLR1 expressed in HEK293 cells co-expressing pGL3-Elam.luc assessed as inhibition of Pam3CSK4-stimulated NF-kappaB activation preincubated for 1 hr followed by Pam3CSK4 stimulation for 5 hrs by luciferase reporter gene assay

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1370.58
1267.47