Assay Report Card

Basic Information

ID: ALA4235565

Type: Binding

Description: Antagonist activity at FLAG-tagged human TLR2/TLR6 expressed in HEK293 cells co-expressing pGL3-Elam.luc assessed as inhibition of Pam2CSK4-stimulated NF-kappaB activation preincubated for 1 hr followed by Pam2CSK4 stimulation for 5 hrs by luciferase reporter gene assay

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1370.58
1267.47