Basic Information
ID: ALA4235566
Type: Binding
Description: Antagonist activity at FLAG-tagged human TLR2/TLR1 expressed in HEK293 cells assessed as inhibition of Pam3CSK4-stimulated MAPK p38 phosphorylation at Thr180/Tyr182 residues at 50 uM preincubated for 1 hr followed by Pam3CSK4 stimulation for 35 mins by immunoblot analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4235566
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1370.58 | ||
| 1267.47 |