ID: ALA4235571
Type: Binding
Description: Antagonist activity at TLR2/TLR1 in human THP1 cells assessed as inhibition of Pam3CSK4-stimulated non-canonical NF-kB pathway by measuring reduction in p52 level at 50 uM preincubated for 1 hr followed by Pam3CSK4 stimulation for 2 hrs by immunoblot analysis
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4235571
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
1370.58 | ||
1267.47 |