Assay Report Card

Basic Information

ID: ALA4235571

Type: Binding

Description: Antagonist activity at TLR2/TLR1 in human THP1 cells assessed as inhibition of Pam3CSK4-stimulated non-canonical NF-kB pathway by measuring reduction in p52 level at 50 uM preincubated for 1 hr followed by Pam3CSK4 stimulation for 2 hrs by immunoblot analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1370.58
1267.47