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Assay Report Card

Basic Information

ID: ALA4235572

Type: Binding

Description: Antagonist activity at TLR2/TLR1 in human PBMC assessed as inhibition of Pam3CSK4-stimulated TNFalpha production at 50 uM preincubated with cells followed by overnight Pam3CSK4 stimulation by ELISA relative to control

Organism: Homo sapiens

Cell type: PBMC

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1370.58
1267.47