Assay Report Card

Basic Information

ID: ALA4235585

Type: Binding

Description: Antagonist activity at FLAG-tagged human TLR2/YFP-tagged TLR1 expressed in HEK293 cells assessed as inhibition of Pam3CSK4-stimulated TLR1/TLR2 heterodimerization at 25 uM preincubated for 1 hr followed by Pam3CSK4 stimulation for 15 mins by immunoblot analysis

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1370.58
1267.47