Basic Information
ID: ALA4235795
Type: Functional
Description: Inhibition of human CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubated for 30 mins followed agonist addition measured after 30 mins by HTRF assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA4235795
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 417.53 | 4.82 | 4.82 |
| 503.55 | 5.06 | 5.06 |
| 346.45 | 2.96 | 2.96 |
| 485.53 | 5.84 | 5.84 |
| 371.46 | 2.83 | 2.83 |
| 473.64 | 6.11 | 6.11 |
| 461.51 | 5.03 | 5.03 |
| 485.53 | 5.84 | 5.84 |
| 503.55 | 5.06 | 5.06 |
| 473.64 | 6.11 | 6.11 |
| 372.45 | 2.23 | 2.23 |
| 398.53 | 3.52 | 3.52 |
| 485.53 | 5.84 | 5.84 |
| 460.52 | 5.96 | 5.96 |
| 415.44 | 3.37 | 3.37 |
| 361.47 | 2.66 | 2.66 |
| 432.55 | 4.19 | 4.19 |
| 418.52 | 3.89 | 3.89 |
| 504.53 | 4.46 | 4.46 |
| 356.45 | 2.53 | 2.53 |
| 372.45 | 2.23 | 2.23 |
| 410.42 | 3.24 | 3.24 |
| 475.57 | 3.84 | 3.84 |
| 461.51 | 5.36 | 5.36 |
| 504.53 | 4.46 | 4.46 |
| 376.48 | 2.97 | 2.97 |
| 486.52 | 5.23 | 5.23 |
| 443.53 | 3.76 | 3.76 |
| 503.55 | 5.06 | 5.06 |
| 372.45 | 2.23 | 2.23 |
| 461.51 | 5.36 | 5.36 |
| 494.62 | 5.55 | 5.55 |
| 344.40 | 1.53 | 1.53 |
| 461.51 | 5.36 | 5.36 |
| 386.48 | 2.62 | 2.62 |
| 376.87 | 2.87 | 2.87 |