Basic Information
ID: ALA4235823
Type: Binding
Description: Inhibition of recombinant human LOX expressed in HEK293 cells at 10 uM using diaminopentane as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr by fluorimetric method relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Lysyl oxidase(ALA2249)
Document: ALA4229522
Inhibition of recombinant human LOX expressed in HEK293 cells at 10 uM using diaminopentane as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr by fluorimetric method relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4235823
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 296.55 | 3.62 | 3.62 |
| 240.44 | 2.06 | 2.06 |
| 127.17 | 0.61 | 0.61 |
| 70.09 | -0.14 | -0.14 |
| 255.30 | 2.44 | 2.44 |
| 239.28 | 2.33 | 2.33 |
| 293.35 | 3.44 | 3.44 |
| 305.34 | 3.59 | 3.59 |
| 406.49 | 5.27 | 5.27 |
| 325.33 | 1.11 | 1.11 |
| 216.28 | 2.83 | 2.83 |
| 333.35 | 2.68 | 2.68 |
| 188.23 | 2.05 | 2.05 |
| 443.49 | 2.50 | 2.50 |