Basic Information
ID: ALA4236562
Type: Binding
Description: Antagonist activity at human TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 mins followed by icilin addition by CCD-camera-based FLASH luminometric analysis
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA4236562
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 492.39 | 6.93 | 6.93 |
| 409.31 | 3.59 | 3.59 |
| 459.31 | 5.46 | 5.46 |
| 414.41 | 4.62 | 4.62 |
| 437.42 | 5.18 | 5.18 |
| 455.36 | 5.04 | 5.04 |
| 421.42 | 5.48 | 5.48 |
| 432.45 | 6.04 | 6.04 |
| 453.32 | 3.87 | 3.87 |
| 475.39 | 6.19 | 6.19 |
| 421.42 | 5.48 | 5.48 |
| 491.39 | 6.07 | 6.07 |
| 425.31 | 3.47 | 3.47 |
| 470.21 | 5.20 | 5.20 |
| 475.39 | 6.19 | 6.19 |
| 413.44 | 5.70 | 5.70 |
| 475.39 | 6.19 | 6.19 |
| 421.42 | 5.48 | 5.48 |
| 407.39 | 5.17 | 5.17 |
| 458.44 | 5.72 | 5.72 |
| 421.42 | 5.36 | 5.36 |
| 493.38 | 6.33 | 6.33 |
| 425.39 | 5.31 | 5.31 |
| 449.35 | 5.51 | 5.51 |
| 442.33 | 5.78 | 5.78 |
| 440.34 | 5.34 | 5.34 |
| 409.31 | 4.58 | 4.58 |
| 391.32 | 3.45 | 3.45 |
| 408.38 | 4.56 | 4.56 |
| 475.39 | 6.19 | 6.19 |
| 425.33 | 5.03 | 5.03 |
| 452.33 | 4.48 | 4.48 |
| 441.33 | 4.33 | 4.33 |
| 469.34 | 4.73 | 4.73 |