Basic Information
ID: ALA4236567
Type: ADME
Description: Transactivation of PXR in human hepatocytes assessed as upregulation of CYP3A4 mRNA expression at 1 uM after 48 hrs relative to rifampicin
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4236567
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 492.39 | 6.93 | 6.93 |
| 409.31 | 3.59 | 3.59 |
| 459.31 | 5.46 | 5.46 |
| 455.36 | 5.04 | 5.04 |
| 453.32 | 3.87 | 3.87 |
| 425.31 | 3.47 | 3.47 |
| 475.39 | 6.19 | 6.19 |
| 493.38 | 6.33 | 6.33 |
| 442.33 | 5.78 | 5.78 |
| 391.32 | 3.45 | 3.45 |
| 452.33 | 4.48 | 4.48 |
| 441.33 | 4.33 | 4.33 |
| 469.34 | 4.73 | 4.73 |