Basic Information
ID: ALA4236657
Type: Binding
Description: Irreversible inhibition of BRD4 in human MV4-11 cells assessed as suppression of IL1RN mRNA levels preincubated for 4 hrs followed by compound washout measured after 4 to 24 hrs post washout by RT-PCR analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MV4-11
Target: Bromodomain-containing protein 4(ALA1163125)
Document: ALA4229554
Irreversible inhibition of BRD4 in human MV4-11 cells assessed as suppression of IL1RN mRNA levels preincubated for 4 hrs followed by compound washout measured after 4 to 24 hrs post washout by RT-PCR analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4236657
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 340.35 | 3.38 | 3.38 |