Basic Information
ID: ALA4236713
Type: Binding
Description: Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ levels preincubated for 5 mins followed by agonist addition by Fuo-4-AM based spectrofluorimetry
Organism: Rattus norvegicus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4236713
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 282.47 | 6.11 | 6.11 |
| 325.54 | 5.13 | 5.13 |
| 347.54 | 5.24 | 5.24 |
| 281.48 | 5.51 | 5.51 |
| 304.47 | 6.22 | 6.22 |
| 299.50 | 4.58 | 4.58 |
| 255.45 | 4.95 | 4.95 |
| 279.47 | 5.29 | 5.29 |
| 419.65 | 7.28 | 7.28 |
| 417.63 | 7.05 | 7.05 |
| 256.43 | 5.55 | 5.55 |
| 283.50 | 5.73 | 5.73 |
| 323.52 | 4.91 | 4.91 |
| 327.55 | 5.36 | 5.36 |
| 338.58 | 7.67 | 7.67 |
| 312.54 | 7.11 | 7.11 |
| 337.59 | 7.07 | 7.07 |
| 371.57 | 5.57 | 5.57 |
| 391.60 | 6.50 | 6.50 |
| 415.62 | 6.83 | 6.83 |
| 381.65 | 6.69 | 6.69 |
| 473.74 | 8.61 | 8.61 |
| 345.53 | 5.02 | 5.02 |
| 355.61 | 6.14 | 6.14 |
| 512.64 | ||
| 625.92 | 8.94 | 8.94 |
| 641.67 | ||
| 554.67 | ||
| 491.78 | 8.18 | 8.18 |
| 336.56 | 7.44 | 7.44 |
| 431.62 | 6.23 | 6.23 |
| 489.77 | 7.95 | 7.95 |
| 652.82 | 6.10 | 6.10 |
| 471.73 | 8.39 | 8.39 |
| 667.71 | ||
| 465.74 | 7.62 | 7.62 |
| 433.63 | 6.03 | 6.03 |
| 536.66 | ||
| 297.48 | 4.35 | 4.35 |
| 594.78 | 6.56 | 6.56 |
| 447.70 | 8.06 | 8.06 |
| 523.78 | 7.16 | 7.16 |
| 404.60 | 6.33 | 6.33 |
| 430.63 | 6.89 | 6.89 |
| 620.82 | 7.12 | 7.12 |
| 311.55 | 6.51 | 6.51 |
| 507.78 | 7.15 | 7.15 |
| 449.63 | 5.43 | 5.43 |
| 672.81 | ||
| 538.68 |