Basic Information
ID: ALA4236724
Type: Binding
Description: Antagonist activity at human dopamine D2 receptor /mGluR5a (unknown origin) expressed in HEK293T cells assessed as inhibition of L-Glu-induced MAPK phosphorylation preincubated for 30 mins followed by agonist stimulation for 10 mins by Western blot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4236724
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 929.11 | 4.03 | 4.03 |
| 803.05 | 6.68 | 6.68 |
| 891.20 | 8.00 | 8.00 |
| 919.25 | 8.78 | 8.78 |
| 930.28 | 8.56 | 8.56 |
| 920.24 | 8.17 | 8.17 |
| 525.72 | 5.49 | 5.49 |
| 958.33 | 9.34 | 9.34 |
| 892.18 | 7.39 | 7.39 |
| 841.00 | 4.00 | 4.00 |