Basic Information
ID: ALA4237183
Type: Functional
Description: Positive allosteric modulation of rat M1 receptor expressed in CHO cells assessed as increase in acetylcholine-induced calcium mobilization pretreated for 2.5 mins followed by acetylcholine addition and measured after 1 min by Fluo-4-AM dye based assay
Organism: Rattus norvegicus
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA4237183
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 432.52 | 3.06 | 3.06 |
| 448.55 | 3.17 | 3.17 |
| 430.51 | 2.87 | 2.87 |
| 458.57 | 3.65 | 3.65 |
| 465.50 | 3.80 | 3.80 |
| 444.54 | 2.99 | 2.99 |
| 441.54 | 3.47 | 3.47 |
| 444.54 | 2.99 | 2.99 |
| 430.51 | 2.87 | 2.87 |
| 432.55 | 4.20 | 4.20 |
| 415.50 | 3.26 | 3.26 |
| 446.58 | 4.32 | 4.32 |
| 442.52 | 2.87 | 2.87 |
| 430.51 | 2.60 | 2.60 |
| 443.55 | 3.60 | 3.60 |
| 430.51 | 2.87 | 2.87 |
| 446.51 | 1.84 | 1.84 |
| 445.52 | 2.44 | 2.44 |
| 432.55 | 4.20 | 4.20 |
| 430.51 | 4.04 | 4.04 |
| 429.52 | 3.47 | 3.47 |
| 444.54 | 3.12 | 3.12 |