Basic Information
ID: ALA4237185
Type: Functional
Description: Positive allosteric modulation of human M1 receptor expressed in CHO cells assessed as increase in acetylcholine-induced calcium mobilization pretreated for 2.5 mins followed by acetylcholine addition and measured after 1 min by Fluo-4-AM dye based assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA4237185
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 448.55 | 3.17 | 3.17 |
| 430.51 | 2.87 | 2.87 |
| 444.54 | 2.99 | 2.99 |
| 443.55 | 3.60 | 3.60 |
| 445.52 | 2.44 | 2.44 |
| 429.52 | 3.47 | 3.47 |