Basic Information
ID: ALA4237190
Type: ADME
Description: Total brain to plasma partition coefficient, Kp in cannulated Sprague-Dawley rat at 0.2 mg/kg, iv administered via jugular vein as cassette dose measured after 0.25 hrs by LC-MS/MS analysis
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Brain/Plasma
Activity Charts
Bioactivity
Activity Types for Assay ALA4237190
Kp
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 448.55 | 3.17 | 3.17 |
| 430.51 | 2.87 | 2.87 |
| 444.54 | 2.99 | 2.99 |
| 444.54 | 2.99 | 2.99 |
| 445.52 | 2.44 | 2.44 |
| 429.52 | 3.47 | 3.47 |