Basic Information
ID: ALA4237203
Type: Binding
Description: Activation of SOS1 in human HeLa cells assessed as increase in RAS-GTP levels after 30 mins by pull-down assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: Son of sevenless homolog 1(ALA2079846)
Document: ALA4229573
Activation of SOS1 in human HeLa cells assessed as increase in RAS-GTP levels after 30 mins by pull-down assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4237203
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 395.26 | 5.34 | 5.34 |
| 346.39 | 4.59 | 4.59 |
| 330.39 | 4.89 | 4.89 |
| 330.39 | 4.89 | 4.89 |
| 350.81 | 5.23 | 5.23 |
| 316.36 | 4.58 | 4.58 |
| 370.86 | 5.77 | 5.77 |
| 344.42 | 5.20 | 5.20 |
| 358.85 | 5.77 | 5.77 |
| 395.26 | 5.34 | 5.34 |
| 399.90 | 4.88 | 4.88 |
| 344.82 | 5.23 | 5.23 |
| 440.95 | 4.79 | 4.79 |
| 384.89 | 6.16 | 6.16 |
| 451.98 | 6.10 | 6.10 |
| 384.89 | 6.16 | 6.16 |
| 344.42 | 5.20 | 5.20 |
| 356.83 | 5.38 | 5.38 |
| 342.81 | 4.99 | 4.99 |
| 437.95 | 5.75 | 5.75 |
| 411.91 | 5.06 | 5.06 |
| 414.92 | 4.75 | 4.75 |
| 370.86 | 5.77 | 5.77 |
| 441.94 | 5.21 | 5.21 |
| 356.83 | 5.38 | 5.38 |
| 368.80 | 5.37 | 5.37 |
| 370.86 | 5.77 | 5.77 |
| 428.94 | 5.96 | 5.96 |
| 385.25 | 5.89 | 5.89 |
| 370.86 | 5.77 | 5.77 |
| 385.87 | 4.84 | 4.84 |
| 346.39 | 4.59 | 4.59 |
| 425.94 | 5.14 | 5.14 |
| 360.42 | 4.63 | 4.63 |
| 356.83 | 5.38 | 5.38 |
| 398.91 | 6.40 | 6.40 |
| 410.84 | 5.31 | 5.31 |
| 415.90 | 4.78 | 4.78 |
| 396.85 | 5.79 | 5.79 |
| 442.97 | 5.35 | 5.35 |
| 438.93 | 6.18 | 6.18 |
| 385.25 | 5.89 | 5.89 |