Basic Information
ID: ALA4251894
Type: ADME
Description: Inhibition of human NaV1.5 expressed in HEK293 cells at -50 mV holding potential after 3 to 5 mins by PatchXpress 7000A electrophysiology method
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4251894
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 465.96 | 4.29 | 4.29 |
| 504.94 | 4.01 | 4.01 |
| 534.49 | 4.44 | 4.44 |
| 474.51 | 3.65 | 3.65 |
| 477.97 | 4.44 | 4.44 |
| 449.50 | 3.78 | 3.78 |
| 463.53 | 4.12 | 4.12 |
| 413.47 | 2.99 | 2.99 |
| 464.52 | 3.39 | 3.39 |
| 522.53 | 4.27 | 4.27 |
| 503.47 | 5.12 | 5.12 |
| 559.50 | 4.31 | 4.31 |
| 504.54 | 3.66 | 3.66 |
| 399.54 | 3.86 | 3.86 |
| 470.50 | 3.36 | 3.36 |
| 491.99 | 4.83 | 4.83 |
| 518.49 | 4.19 | 4.19 |
| 466.94 | 3.69 | 3.69 |
| 464.52 | 3.39 | 3.39 |
| 463.48 | 3.63 | 3.63 |
| 456.52 | 3.51 | 3.51 |
| 551.93 | 4.35 | 4.35 |