Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux by measuri...

Basic Information

ID: ALA4252012

Type: Binding

Description: Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux by measuring leftward fold shift in glycine EC50 at 3.2 uM measured for 4 mins by Schild plot analysis

Format: BAO_0000219

Organism: Homo sapiens

Target:  Glycine receptor alpha-3/beta(ALA4106144)

Document:  ALA4251550

Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux by measuring leftward fold shift in glycine EC50 at 3.2 uM measured for 4 mins by Schild plot analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
410.842.232.23