Basic Information
ID: ALA4252021
Type: Binding
Description: Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured for 4 mins in presence of GlyRs inhibitor strychnine by FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Glycine receptor alpha-3/beta(ALA4106144)
Document: ALA4251550
Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured for 4 mins in presence of GlyRs inhibitor strychnine by FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4252021
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 490.49 | 4.08 | 4.08 |
| 450.43 | 3.20 | 3.20 |