Basic Information
ID: ALA4252246
Type: Binding
Description: Antagonist activity at P2X7R in Swiss Webster mouse peritoneal macrophages assessed as inhibition of ATP-induced propidium iodide uptake preincubated for 10 mins followed by ATP induction measured after 25 mins by fluorescence assay
Organism: Mus musculus
Strain: Swiss Webster
Activity Charts
Bioactivity
Activity Types for Assay ALA4252246
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 174.15 | 1.51 | 1.51 |
| 474.57 | 3.82 | 3.82 |
| 264.28 | 3.34 | 3.34 |
| 854.04 | 9.31 | 9.31 |
| 250.25 | 3.03 | 3.03 |
| 268.24 | 3.17 | 3.17 |
| 280.28 | 3.04 | 3.04 |
| 275.26 | 2.91 | 2.91 |
| 253.05 | 2.23 | 2.23 |
| 300.05 | 2.27 | 2.27 |
| 280.28 | 3.04 | 3.04 |