Basic Information
ID: ALA4252251
Type: Binding
Description: Antagonist activity at human P2X7R expressed in HEK293 cells assessed as inhibition of ATP-induced ethidium iodide uptake preincubated for 10 mins followed by ATP induction measured after 25 mins by fluorescence assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4252251
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 474.57 | 3.82 | 3.82 |
| 854.04 | 9.31 | 9.31 |
| 250.25 | 3.03 | 3.03 |
| 253.05 | 2.23 | 2.23 |
| 300.05 | 2.27 | 2.27 |