Basic Information
ID: ALA4252297
Type: Binding
Description: Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based fluorescence assay
Organism: dengue virus type 3
Activity Charts
Bioactivity
Activity Types for Assay ALA4252297
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 541.59 | 3.44 | 3.44 |
| 558.04 | 3.96 | 3.96 |
| 537.62 | 3.61 | 3.61 |
| 396.26 | 4.33 | 4.33 |
| 449.53 | 5.69 | 5.69 |
| 486.34 | 5.11 | 5.11 |
| 472.32 | 5.15 | 5.15 |
| 486.34 | 5.18 | 5.18 |
| 421.47 | 4.95 | 4.95 |
| 547.34 | 5.07 | 5.07 |
| 493.29 | 4.65 | 4.65 |
| 472.32 | 5.15 | 5.15 |
| 547.34 | 5.07 | 5.07 |
| 422.28 | 5.47 | 5.47 |
| 472.32 | 5.15 | 5.15 |
| 382.24 | 3.94 | 3.94 |
| 508.30 | 5.43 | 5.43 |
| 517.31 | 5.06 | 5.06 |
| 448.29 | 4.74 | 4.74 |
| 472.32 | 4.41 | 4.41 |
| 423.45 | 4.40 | 4.40 |
| 508.30 | 5.43 | 5.43 |
| 411.41 | 4.53 | 4.53 |