Basic Information
ID: ALA4253672
Type: Binding
Description: Inhibition of GST-tagged LSD1 (2 to 852 residues) (unknown origin) expressed in baculovirus infected sf9 cells preincubated for 15 mins followed by H3K4me2 substrate addition measured after 60 mins by amplex red reagent based HRP enzyme coupled fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4253672
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 133.19 | 1.50 | 1.50 |
| 223.32 | 3.33 | 3.33 |
| 253.34 | 3.34 | 3.34 |
| 271.79 | 4.29 | 4.29 |
| 241.31 | 3.47 | 3.47 |
| 268.32 | 3.24 | 3.24 |
| 257.76 | 3.99 | 3.99 |
| 320.20 | 4.23 | 4.23 |
| 408.34 | 5.67 | 5.67 |
| 302.40 | 1.98 | 1.98 |
| 268.32 | 3.24 | 3.24 |
| 280.37 | 3.29 | 3.29 |
| 329.44 | 4.91 | 4.91 |
| 260.32 | 3.62 | 3.62 |
| 292.21 | 4.64 | 4.64 |
| 349.21 | 3.94 | 3.94 |
| 268.36 | 2.98 | 2.98 |
| 302.21 | 4.09 | 4.09 |
| 408.34 | 5.67 | 5.67 |
| 267.37 | 3.59 | 3.59 |
| 299.42 | 5.00 | 5.00 |
| 279.43 | 4.63 | 4.63 |
| 253.34 | 3.34 | 3.34 |
| 302.76 | 3.89 | 3.89 |
| 283.37 | 3.35 | 3.35 |
| 259.30 | 3.61 | 3.61 |
| 257.76 | 3.99 | 3.99 |
| 241.31 | 3.47 | 3.47 |
| 266.34 | 2.43 | 2.43 |
| 329.44 | 4.91 | 4.91 |
| 251.37 | 3.89 | 3.89 |
| 253.34 | 3.34 | 3.34 |
| 316.43 | 2.24 | 2.24 |
| 257.76 | 3.99 | 3.99 |
| 302.21 | 4.09 | 4.09 |
| 268.32 | 3.24 | 3.24 |
| 292.21 | 4.64 | 4.64 |
| 254.33 | 2.74 | 2.74 |
| 224.31 | 2.73 | 2.73 |
| 299.42 | 5.00 | 5.00 |
| 266.39 | 3.40 | 3.40 |
| 276.38 | 3.82 | 3.82 |
| 244.25 | 3.16 | 3.16 |
| 241.31 | 3.47 | 3.47 |
| 302.21 | 4.09 | 4.09 |
| 266.34 | 2.43 | 2.43 |