Basic Information
ID: ALA4253710
Type: Binding
Description: Inhibition of human TNAP expressed in COS7 cells preincubated for 5 to 7 mins followed by CDP-star substrate addition measured after 15 to 20 mins by luminescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4253710
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 180.17 | -1.04 | -1.04 |
| 204.30 | 2.15 | 2.15 |
| 306.31 | 2.77 | 2.77 |
| 327.29 | 2.85 | 2.85 |
| 342.26 | 2.75 | 2.75 |
| 265.22 | 0.48 | 0.48 |
| 325.32 | 3.45 | 3.45 |
| 315.25 | 2.98 | 2.98 |
| 292.29 | 2.38 | 2.38 |
| 276.24 | 1.77 | 1.77 |
| 342.30 | 2.92 | 2.92 |
| 373.36 | 4.50 | 4.50 |
| 297.26 | 2.84 | 2.84 |
| 341.31 | 3.24 | 3.24 |
| 307.30 | 1.14 | 1.14 |
| 325.32 | 3.45 | 3.45 |
| 381.26 | 3.74 | 3.74 |
| 354.36 | 4.04 | 4.04 |
| 322.27 | 2.71 | 2.71 |
| 357.31 | 2.85 | 2.85 |
| 348.39 | 3.58 | 3.58 |
| 315.25 | 2.98 | 2.98 |
| 325.32 | 3.40 | 3.40 |
| 327.29 | 2.50 | 2.50 |
| 327.29 | 2.85 | 2.85 |
| 311.29 | 3.15 | 3.15 |
| 278.26 | 1.99 | 1.99 |
| 341.31 | 3.24 | 3.24 |
| 365.26 | 3.86 | 3.86 |
| 356.33 | 3.31 | 3.31 |