Basic Information
ID: ALA4254056
Type: Binding
Description: Inhibition of human MDR1 expressed in MDCK-MDR1 cells assessed as calcein cell accumulation after 30 mins by spectrofluorimetry
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MDCK-MDR1
Target: P-glycoprotein 1(ALA4302)
Document: ALA4251616
Inhibition of human MDR1 expressed in MDCK-MDR1 cells assessed as calcein cell accumulation after 30 mins by spectrofluorimetry: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4254056
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 339.53 | 4.37 | 4.37 |
| 364.49 | 4.50 | 4.50 |
| 234.33 | 1.25 | 1.25 |
| 206.27 | 0.65 | 0.65 |
| 238.42 | 3.13 | 3.13 |
| 456.70 | 3.38 | 3.38 |
| 481.67 | 3.50 | 3.50 |
| 263.38 | 3.25 | 3.25 |
| 495.65 | 3.14 | 3.14 |