Basic Information
ID: ALA4255910
Type: Binding
Description: Inhibition of STAT3 DNA binding activity in mouse NIH/3T3 nuclear extract preincubated for 30 mins followed by [32P]hSIE addition measured after 30 mins by electrophoretic mobility shift assay
Format: BAO_0000357
Organism: Mus musculus
Target: Signal transducer and activator of transcription 3(ALA5402)
Document: ALA4251703
Inhibition of STAT3 DNA binding activity in mouse NIH/3T3 nuclear extract preincubated for 30 mins followed by [32P]hSIE addition measured after 30 mins by electrophoretic mobility shift assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4255910
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 550.68 | 5.30 | 5.30 |
| 626.60 | 5.69 | 5.69 |
| 610.60 | 5.98 | 5.98 |
| 625.62 | 5.40 | 5.40 |
| 652.64 | 6.08 | 6.08 |
| 662.61 | 6.08 | 6.08 |
| 655.64 | 4.76 | 4.76 |
| 572.63 | 5.27 | 5.27 |
| 652.64 | 6.22 | 6.22 |
| 640.58 | 4.68 | 4.68 |
| 645.05 | 6.64 | 6.64 |
| 674.09 | 6.44 | 6.44 |
| 635.66 | 5.92 | 5.92 |
| 624.63 | 6.29 | 6.29 |
| 611.59 | 5.38 | 5.38 |
| 616.58 | 6.67 | 6.67 |
| 662.58 | 5.93 | 5.93 |
| 638.66 | 6.68 | 6.68 |
| 627.59 | 4.11 | 4.11 |
| 655.64 | 5.01 | 5.01 |
| 656.63 | 5.05 | 5.05 |
| 672.64 | 7.03 | 7.03 |
| 652.64 | 6.08 | 6.08 |
| 670.65 | 5.44 | 5.44 |
| 624.63 | 6.37 | 6.37 |
| 638.61 | 5.83 | 5.83 |
| 684.64 | 5.53 | 5.53 |
| 576.56 | 6.50 | 6.50 |
| 645.05 | 6.64 | 6.64 |
| 624.63 | 5.91 | 5.91 |
| 634.65 | 6.08 | 6.08 |
| 622.61 | 6.28 | 6.28 |
| 590.62 | 5.41 | 5.41 |
| 652.68 | 7.07 | 7.07 |
| 642.62 | 6.51 | 6.51 |
| 643.59 | 3.95 | 3.95 |
| 670.65 | 5.44 | 5.44 |
| 690.63 | 6.71 | 6.71 |
| 590.55 | 6.14 | 6.14 |
| 642.62 | 6.51 | 6.51 |
| 611.59 | 4.92 | 4.92 |
| 639.64 | 5.79 | 5.79 |
| 654.61 | 5.07 | 5.07 |
| 655.64 | 5.50 | 5.50 |
| 642.60 | 4.92 | 4.92 |
| 601.55 | 4.97 | 4.97 |
| 671.08 | 7.17 | 7.17 |
| 602.60 | 7.03 | 7.03 |
| 654.65 | 6.47 | 6.47 |
| 659.07 | 7.02 | 7.02 |
| 632.58 | 5.98 | 5.98 |
| 624.63 | 6.37 | 6.37 |
| 655.64 | 5.01 | 5.01 |
| 572.63 | 5.27 | 5.27 |
| 654.63 | 6.65 | 6.65 |
| 590.62 | 5.41 | 5.41 |
| 659.07 | 7.02 | 7.02 |
| 640.63 | 6.08 | 6.08 |
| 684.64 | 5.53 | 5.53 |
| 616.66 | 5.94 | 5.94 |
| 640.63 | 5.34 | 5.34 |
| 652.68 | 6.99 | 6.99 |
| 638.66 | 6.60 | 6.60 |
| 627.59 | 4.62 | 4.62 |
| 627.59 | 5.08 | 5.08 |
| 656.63 | 5.05 | 5.05 |
| 640.63 | 6.08 | 6.08 |
| 612.57 | 4.83 | 4.83 |
| 670.65 | 5.44 | 5.44 |
| 660.61 | 6.65 | 6.65 |
| 652.64 | 6.22 | 6.22 |
| 620.64 | 6.55 | 6.55 |
| 670.65 | 5.44 | 5.44 |
| 664.58 | 4.92 | 4.92 |
| 537.64 | 4.39 | 4.39 |
| 628.57 | 4.53 | 4.53 |
| 624.63 | 6.37 | 6.37 |
| 654.65 | 6.47 | 6.47 |
| 667.65 | 5.64 | 5.64 |
| 590.62 | 5.41 | 5.41 |
| 624.63 | 6.29 | 6.29 |
| 601.55 | 4.97 | 4.97 |