Basic Information
ID: ALA4255965
Type: Binding
Description: Inhibition of human His6-tagged BRD4 BD1 (N44 to E168 residues) expressed in Escherichia coli BL21 (DE3) cells at 20 uM using H-SGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac)RHRK-Biotin-OH as substrate after 2.5 hrs by AlphaScreen assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Target: Bromodomain-containing protein 4(ALA1163125)
Document: ALA4251705
Inhibition of human His6-tagged BRD4 BD1 (N44 to E168 residues) expressed in Escherichia coli BL21 (DE3) cells at 20 uM using H-SGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac)RHRK-Biotin-OH as substrate after 2.5 hrs by AlphaScreen assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4255965
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 457.00 | 5.53 | 5.53 |
| 369.35 | 2.27 | 2.27 |
| 339.40 | 2.05 | 2.05 |
| 384.82 | 3.39 | 3.39 |
| 338.43 | 2.87 | 2.87 |
| 396.85 | 3.26 | 3.26 |
| 298.36 | 1.95 | 1.95 |
| 510.41 | 3.97 | 3.97 |
| 350.37 | 2.74 | 2.74 |
| 346.41 | 2.91 | 2.91 |
| 471.33 | 3.38 | 3.38 |
| 475.75 | 4.02 | 4.02 |
| 347.40 | 2.30 | 2.30 |
| 390.42 | 2.38 | 2.38 |
| 457.30 | 3.07 | 3.07 |
| 338.41 | 2.66 | 2.66 |
| 313.38 | 1.73 | 1.73 |
| 441.30 | 3.37 | 3.37 |
| 384.82 | 3.39 | 3.39 |
| 312.39 | 2.34 | 2.34 |
| 411.28 | 3.36 | 3.36 |
| 484.37 | 3.43 | 3.43 |
| 368.36 | 2.88 | 2.88 |
| 351.36 | 2.13 | 2.13 |
| 526.41 | 3.20 | 3.20 |
| 332.38 | 2.60 | 2.60 |