ID: ALA4255966
Type: Binding
Description: Inhibition of human His6-tagged BRD4 BD1 (N44 to E168 residues) expressed in Escherichia coli BL21 (DE3) cells using H-SGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac)RHRK-Biotin-OH as substrate after 2.5 hrs by AlphaScreen assay
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4255966
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
457.00 | 5.53 | 5.53 |
369.35 | 2.27 | 2.27 |
339.40 | 2.05 | 2.05 |
384.82 | 3.39 | 3.39 |
338.43 | 2.87 | 2.87 |
396.85 | 3.26 | 3.26 |
298.36 | 1.95 | 1.95 |
510.41 | 3.97 | 3.97 |
350.37 | 2.74 | 2.74 |
346.41 | 2.91 | 2.91 |
471.33 | 3.38 | 3.38 |
475.75 | 4.02 | 4.02 |
347.40 | 2.30 | 2.30 |
390.42 | 2.38 | 2.38 |
457.30 | 3.07 | 3.07 |
338.41 | 2.66 | 2.66 |
313.38 | 1.73 | 1.73 |
441.30 | 3.37 | 3.37 |
384.82 | 3.39 | 3.39 |
312.39 | 2.34 | 2.34 |
411.28 | 3.36 | 3.36 |
484.37 | 3.43 | 3.43 |
368.36 | 2.88 | 2.88 |
351.36 | 2.13 | 2.13 |
526.41 | 3.20 | 3.20 |
332.38 | 2.60 | 2.60 |