Inhibition of human His6-tagged BRD4 BD1 (N44 to E168 residues) expressed in Escherichia coli BL21 (DE3) cells using H-SGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac...

Basic Information

ID: ALA4255966

Type: Binding

Description: Inhibition of human His6-tagged BRD4 BD1 (N44 to E168 residues) expressed in Escherichia coli BL21 (DE3) cells using H-SGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac)RHRK-Biotin-OH as substrate after 2.5 hrs by AlphaScreen assay

Format: BAO_0000219

Organism: Homo sapiens

Target: Bromodomain-containing protein 4(ALA1163125)

Document: ALA4251705

Inhibition of human His6-tagged BRD4 BD1 (N44 to E168 residues) expressed in Escherichia coli BL21 (DE3) cells using H-SGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac)RHRK-Biotin-OH as substrate after 2.5 hrs by AlphaScreen assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4255966

IC50

Total(26)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
457.00	5.53	5.53
369.35	2.27	2.27
339.40	2.05	2.05
384.82	3.39	3.39
338.43	2.87	2.87
396.85	3.26	3.26
298.36	1.95	1.95
510.41	3.97	3.97
350.37	2.74	2.74
346.41	2.91	2.91
471.33	3.38	3.38
475.75	4.02	4.02
347.40	2.30	2.30
390.42	2.38	2.38
457.30	3.07	3.07
338.41	2.66	2.66
313.38	1.73	1.73
441.30	3.37	3.37
384.82	3.39	3.39
312.39	2.34	2.34
411.28	3.36	3.36
484.37	3.43	3.43
368.36	2.88	2.88
351.36	2.13	2.13
526.41	3.20	3.20
332.38	2.60	2.60