Assay Report Card

Basic Information

ID: ALA4256352

Type: Binding

Description: Inhibition of NADPH-reduced TrxR1 in human GM02152 cells assessed as suppression of insulin reduction by measuring enzyme rate using Trx as substrate pretreated for 30 mins followed by Trx addition for 30 mins and subsequent eosin-labelled bovine insulin addition measured every 5 mins up to 15 mins by fluorescence assay relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
550.653.703.70