Assay Report Card

Basic Information

ID: ALA4256357

Type: Binding

Description: Irreversible inhibition of NADPH-reduced recombinant rat TrxR1 expressed in Escherichia coli harboring gor mutant assessed as suppression of DTNB reduction at 2 uM pretreated for 1 hr followed by NADPH addition for 30 mins and subsequent DTNB addition measured every 5 mins for 1 hr

Organism: Rattus norvegicus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
550.653.703.70