Assay Report Card

Basic Information

ID: ALA4256359

Type: Binding

Description: Inhibition of NADPH-reduced recombinant rat TrxR1 expressed in Escherichia coli harboring gor mutant assessed as suppression of insulin reduction at 20 uM using Trx as substrate pretreated for 30 mins followed by Trx addition for 30 mins and subsequent eosin-labelled bovine insulin addition measured every 5 mins for 1 hr by fluorescence assay

Organism: Rattus norvegicus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
550.653.703.70