Basic Information
ID: ALA4256451
Type: Binding
Description: Inhibition of bacterial NDM1 expressed in Escherichia coli DH10B assessed as potentiation of cefazolin-induced antibacterial activity by measuring cefazolin MIC at 32 ug/ml after 16 hrs by broth micro-dilution method (Rvb = 8 ug/ml)
Organism: Bacteria
Activity Charts
Bioactivity
Activity Types for Assay ALA4256451
MIC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 279.34 | 1.97 | 1.97 |
| 329.40 | 3.13 | 3.13 |
| 341.41 | 3.79 | 3.79 |
| 359.40 | 3.93 | 3.93 |
| 285.37 | 2.03 | 2.03 |
| 313.79 | 2.63 | 2.63 |
| 329.40 | 3.13 | 3.13 |
| 347.34 | 2.99 | 2.99 |
| 348.23 | 3.28 | 3.28 |
| 324.34 | 1.88 | 1.88 |
| 297.33 | 2.11 | 2.11 |
| 309.37 | 1.98 | 1.98 |
| 269.30 | 1.57 | 1.57 |
| 280.33 | 1.37 | 1.37 |
| 210.25 | 2.05 | 2.05 |
| 391.47 | 4.94 | 4.94 |
| 371.44 | 3.80 | 3.80 |
| 386.41 | 3.70 | 3.70 |
| 369.34 | 1.79 | 1.79 |
| 409.41 | 4.81 | 4.81 |
| 342.40 | 3.19 | 3.19 |
| 391.47 | 4.94 | 4.94 |
| 410.30 | 5.10 | 5.10 |
| 375.86 | 4.44 | 4.44 |
| 331.37 | 3.38 | 3.38 |
| 347.44 | 3.85 | 3.85 |
| 431.41 | 3.61 | 3.61 |