Basic Information
ID: ALA4256562
Type: Binding
Description: Inhibition of recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) expressed in human LS174T cells assessed as reduction in doxycycline-induced NICD expression after 12 hrs by Bright-Glo luciferase reporter gene assay
Organism: Mus musculus
Cell type: LS174T
Activity Charts
Bioactivity
Activity Types for Assay ALA4256562
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 576.73 | 3.68 | 3.68 |
| 374.52 | 3.60 | 3.60 |
| 518.69 | 4.14 | 4.14 |
| 534.69 | 3.25 | 3.25 |
| 520.66 | 3.07 | 3.07 |
| 516.68 | 4.06 | 4.06 |
| 576.73 | 3.68 | 3.68 |
| 534.69 | 3.11 | 3.11 |