Basic Information
ID: ALA4256752
Type: Binding
Description: Inhibition of NLRP3 in mouse J774A.1 cells assessed as reduction in LPS-stimulated IL-1beta levels pre-incubated with LPS for 4.5 hrs followed by incubation for 30 mins in presence of ATP and measured after 30 mins by ELISA
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4256752
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 382.87 | 2.23 | 2.23 |
| 382.87 | 2.23 | 2.23 |
| 493.41 | 4.45 | 4.45 |
| 481.06 | 4.91 | 4.91 |
| 488.99 | 3.81 | 3.81 |
| 436.96 | 3.50 | 3.50 |
| 382.87 | 2.23 | 2.23 |
| 352.84 | 2.22 | 2.22 |
| 410.92 | 3.01 | 3.01 |
| 408.91 | 2.72 | 2.72 |
| 396.90 | 2.62 | 2.62 |
| 424.95 | 3.35 | 3.35 |
| 318.40 | 1.57 | 1.57 |
| 424.95 | 3.40 | 3.40 |
| 458.97 | 3.80 | 3.80 |
| 437.95 | 1.92 | 1.92 |
| 382.87 | 2.23 | 2.23 |
| 526.96 | 4.82 | 4.82 |
| 348.42 | 1.58 | 1.58 |
| 474.97 | 3.51 | 3.51 |
| 422.93 | 3.11 | 3.11 |
| 410.92 | 3.01 | 3.01 |
| 382.87 | 2.23 | 2.23 |
| 368.84 | 1.93 | 1.93 |
| 453.00 | 4.13 | 4.13 |
| 472.99 | 3.84 | 3.84 |
| 444.94 | 4.12 | 4.12 |
| 438.93 | 2.34 | 2.34 |
| 382.87 | 2.23 | 2.23 |