Basic Information
ID: ALA4256753
Type: Binding
Description: Inhibition of NLRP3 in mouse BMDM assessed as reduction in LPS-stimulated IL-1beta levels pre-incubated with LPS for 4.5 hrs followed by incubation for 30 mins in presence of ATP and measured after 30 mins by ELISA
Organism: Mus musculus
Cell type: BMDM
Activity Charts
Bioactivity
Activity Types for Assay ALA4256753
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 481.06 | 4.91 | 4.91 |
| 488.99 | 3.81 | 3.81 |