Basic Information
ID: ALA4256757
Type: Functional
Description: In-vivo inhibition of NLRP3 inflammasome in C57BL/6 mouse assessed as reduction in LPS-induced IL-1beta levels at 0.5 mg/kg, ip pre-treated for 1 hr followed by LPS stimulation for 2.5 hrs by ELISA
Organism: Mus musculus
Strain: C57BL/6
Activity Charts
Bioactivity
Activity Types for Assay ALA4256757
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 481.06 | 4.91 | 4.91 |
| 488.99 | 3.81 | 3.81 |
| 402.52 | 4.06 | 4.06 |