Basic Information
ID: ALA4256853
Type: Functional
Description: Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins followed by 5-oxo-ETE addition measured after 1 min by fluorescence assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Oxoeicosanoid receptor 1(ALA1628461)
Document: ALA4251757
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins followed by 5-oxo-ETE addition measured after 1 min by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4256853
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 363.88 | 5.56 | 5.56 |
| 377.91 | 5.64 | 5.64 |
| 377.91 | 5.64 | 5.64 |
| 470.01 | 6.35 | 6.35 |
| 439.98 | 6.78 | 6.78 |
| 431.88 | 6.18 | 6.18 |
| 425.96 | 6.08 | 6.08 |
| 397.90 | 5.61 | 5.61 |
| 470.01 | 6.35 | 6.35 |
| 425.96 | 6.39 | 6.39 |
| 454.01 | 6.86 | 6.86 |
| 439.98 | 6.47 | 6.47 |
| 470.01 | 6.35 | 6.35 |
| 411.93 | 5.69 | 5.69 |
| 454.01 | 6.86 | 6.86 |
| 411.93 | 6.00 | 6.00 |
| 454.01 | 6.86 | 6.86 |
| 470.01 | 6.35 | 6.35 |