Basic Information
ID: ALA4256949
Type: Binding
Description: Inhibition of recombinant human C-terminal FLAG-tagged JARID1A (1 to 1090 residues) expressed in baculovirus infected sf9 cells using H3K4me3-biotin peptide as substrate after 30 mins in presence of alpha-ketoglutaric acid by LANCE TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4256949
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 329.74 | 3.20 | 3.20 |
| 343.77 | 3.51 | 3.51 |
| 357.34 | 2.22 | 2.22 |
| 335.36 | 3.42 | 3.42 |
| 313.29 | 2.68 | 2.68 |
| 295.30 | 2.54 | 2.54 |
| 399.83 | 3.99 | 3.99 |
| 329.74 | 3.29 | 3.29 |
| 327.31 | 2.99 | 2.99 |
| 327.31 | 3.24 | 3.24 |
| 341.34 | 3.25 | 3.25 |
| 283.26 | 2.77 | 2.77 |
| 265.27 | 2.63 | 2.63 |
| 309.33 | 2.95 | 2.95 |
| 374.19 | 3.31 | 3.31 |
| 343.36 | 2.04 | 2.04 |
| 323.35 | 3.11 | 3.11 |
| 313.29 | 2.68 | 2.68 |
| 435.87 | 4.78 | 4.78 |
| 281.27 | 2.34 | 2.34 |
| 283.26 | 2.77 | 2.77 |
| 279.30 | 2.94 | 2.94 |
| 309.32 | 2.85 | 2.85 |
| 359.77 | 3.21 | 3.21 |
| 295.30 | 2.65 | 2.65 |
| 281.27 | 2.34 | 2.34 |
| 363.30 | 3.56 | 3.56 |
| 347.73 | 3.34 | 3.34 |
| 325.32 | 2.55 | 2.55 |
| 313.29 | 2.68 | 2.68 |
| 384.41 | 2.79 | 2.79 |
| 301.25 | 2.91 | 2.91 |
| 301.25 | 2.91 | 2.91 |
| 373.80 | 3.60 | 3.60 |
| 320.31 | 2.42 | 2.42 |
| 295.30 | 2.26 | 2.26 |
| 397.74 | 4.22 | 4.22 |
| 249.23 | 0.82 | 0.82 |
| 331.28 | 2.82 | 2.82 |
| 334.34 | 2.72 | 2.72 |
| 341.34 | 3.25 | 3.25 |
| 451.89 | 5.12 | 5.12 |
| 311.30 | 2.25 | 2.25 |
| 315.72 | 2.99 | 2.99 |
| 296.29 | 1.94 | 1.94 |
| 293.33 | 3.25 | 3.25 |
| 337.38 | 3.42 | 3.42 |
| 353.35 | 3.56 | 3.56 |
| 327.31 | 2.99 | 2.99 |
| 337.34 | 2.48 | 2.48 |
| 347.73 | 3.34 | 3.34 |
| 296.29 | 1.94 | 1.94 |
| 359.36 | 1.74 | 1.74 |
| 203.20 | 1.27 | 1.27 |
| 401.85 | 4.23 | 4.23 |
| 293.33 | 2.75 | 2.75 |
| 388.22 | 3.62 | 3.62 |
| 344.17 | 3.40 | 3.40 |
| 345.31 | 3.13 | 3.13 |
| 387.82 | 3.99 | 3.99 |
| 293.33 | 2.75 | 2.75 |
| 404.22 | 3.32 | 3.32 |
| 337.33 | 3.17 | 3.17 |
| 327.31 | 2.99 | 2.99 |
| 308.34 | 2.70 | 2.70 |
| 329.74 | 3.20 | 3.20 |
| 357.80 | 3.76 | 3.76 |
| 279.30 | 2.94 | 2.94 |
| 369.81 | 4.08 | 4.08 |
| 343.77 | 3.51 | 3.51 |
| 334.34 | 2.72 | 2.72 |
| 347.73 | 3.34 | 3.34 |
| 307.35 | 3.50 | 3.50 |
| 364.19 | 3.85 | 3.85 |
| 305.30 | 2.51 | 2.51 |
| 273.29 | 2.33 | 2.33 |
| 279.30 | 2.56 | 2.56 |
| 365.39 | 3.26 | 3.26 |
| 364.19 | 3.85 | 3.85 |
| 233.23 | 1.28 | 1.28 |
| 357.80 | 3.76 | 3.76 |
| 335.32 | 2.42 | 2.42 |
| 279.30 | 2.56 | 2.56 |
| 245.28 | 2.31 | 2.31 |
| 343.77 | 3.51 | 3.51 |
| 378.41 | 2.29 | 2.29 |
| 219.20 | 0.98 | 0.98 |
| 279.30 | 2.94 | 2.94 |
| 294.31 | 2.52 | 2.52 |
| 355.78 | 3.69 | 3.69 |
| 348.36 | 2.98 | 2.98 |
| 245.28 | 2.31 | 2.31 |
| 327.32 | 2.99 | 2.99 |
| 354.39 | 2.78 | 2.78 |
| 401.85 | 4.38 | 4.38 |
| 205.17 | 0.67 | 0.67 |
| 353.35 | 3.56 | 3.56 |
| 325.32 | 2.55 | 2.55 |
| 320.31 | 2.42 | 2.42 |
| 399.83 | 3.99 | 3.99 |
| 353.35 | 3.56 | 3.56 |
| 247.25 | 1.62 | 1.62 |
| 309.32 | 2.85 | 2.85 |
| 315.72 | 2.99 | 2.99 |
| 369.81 | 4.08 | 4.08 |
| 315.72 | 2.99 | 2.99 |
| 427.77 | 4.14 | 4.14 |
| 299.26 | 2.48 | 2.48 |
| 339.35 | 2.86 | 2.86 |
| 374.19 | 3.31 | 3.31 |
| 315.72 | 2.99 | 2.99 |
| 453.86 | 4.92 | 4.92 |
| 331.28 | 2.82 | 2.82 |
| 349.35 | 2.43 | 2.43 |
| 453.86 | 4.92 | 4.92 |
| 435.22 | 3.46 | 3.46 |
| 323.35 | 3.16 | 3.16 |
| 311.30 | 2.25 | 2.25 |
| 437.40 | 4.40 | 4.40 |
| 349.35 | 2.43 | 2.43 |
| 451.22 | 3.16 | 3.16 |
| 433.41 | 4.99 | 4.99 |
| 339.33 | 3.17 | 3.17 |
| 357.80 | 3.76 | 3.76 |
| 341.34 | 3.25 | 3.25 |
| 309.27 | 2.39 | 2.39 |
| 427.77 | 4.14 | 4.14 |
| 401.85 | 4.38 | 4.38 |
| 341.34 | 3.25 | 3.25 |
| 437.40 | 4.40 | 4.40 |
| 233.23 | 1.29 | 1.29 |
| 449.89 | 5.34 | 5.34 |
| 245.24 | 1.55 | 1.55 |
| 295.30 | 2.65 | 2.65 |
| 403.82 | 3.22 | 3.22 |
| 433.44 | 4.82 | 4.82 |
| 449.87 | 5.51 | 5.51 |
| 369.81 | 4.08 | 4.08 |
| 435.43 | 4.61 | 4.61 |