Assay Report Card

Basic Information

ID: ALA4256951

Type: Binding

Description: Inhibition of recombinant human N-terminal GST-tagged JMJD2C (2 to 372 residues) expressed in baculovirus infected sf9 cells using H3K9me3-biotin peptide as substrate after 30 mins in presence of alpha-ketoglutaric acid by LANCE TR-FRET assay

Organism: Homo sapiens

Activity Charts

Bioactivity

Activity Types for Assay ALA4256951

IC50

Total(154)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
329.74	3.20	3.20
343.77	3.51	3.51
357.34	2.22	2.22
335.36	3.42	3.42
313.29	2.68	2.68
295.30	2.54	2.54
399.83	3.99	3.99
329.74	3.29	3.29
327.31	2.99	2.99
327.31	3.24	3.24
341.34	3.25	3.25
283.26	2.77	2.77
265.27	2.63	2.63
309.33	2.95	2.95
374.19	3.31	3.31
343.36	2.04	2.04
323.35	3.11	3.11
313.29	2.68	2.68
435.87	4.78	4.78
281.27	2.34	2.34
283.26	2.77	2.77
279.30	2.94	2.94
309.32	2.85	2.85
359.77	3.21	3.21
295.30	2.65	2.65
281.27	2.34	2.34
363.30	3.56	3.56
347.73	3.34	3.34
325.32	2.55	2.55
313.29	2.68	2.68
384.41	2.79	2.79
301.25	2.91	2.91
301.25	2.91	2.91
373.80	3.60	3.60
320.31	2.42	2.42
295.30	2.26	2.26
353.77	2.40	2.40
397.74	4.22	4.22
309.32	2.82	2.82
327.31	2.71	2.71
249.23	0.82	0.82
331.28	2.82	2.82
334.34	2.72	2.72
341.34	3.25	3.25
451.89	5.12	5.12
311.30	2.25	2.25
315.72	2.99	2.99
296.29	1.94	1.94
293.33	3.25	3.25
337.38	3.42	3.42
353.35	3.56	3.56
327.31	2.99	2.99
337.34	2.48	2.48
347.73	3.34	3.34
296.29	1.94	1.94
359.36	1.74	1.74
203.20	1.27	1.27
401.85	4.23	4.23
293.33	2.75	2.75
388.22	3.62	3.62
364.19	3.57	3.57
344.17	3.40	3.40
345.31	3.13	3.13
387.82	3.99	3.99
293.33	2.75	2.75
404.22	3.32	3.32
337.33	3.17	3.17
327.31	2.99	2.99
308.34	2.70	2.70
329.74	3.20	3.20
357.80	3.76	3.76
279.30	2.94	2.94
369.81	4.08	4.08
331.28	2.54	2.54
343.77	3.51	3.51
334.34	2.72	2.72
347.73	3.34	3.34
307.35	3.50	3.50
364.19	3.85	3.85
331.28	2.54	2.54
305.30	2.51	2.51
273.29	2.33	2.33
279.30	2.56	2.56
365.39	3.26	3.26
364.19	3.85	3.85
233.23	1.28	1.28
357.80	3.76	3.76
333.36	2.30	2.30
335.32	2.42	2.42
279.30	2.56	2.56
245.28	2.31	2.31
343.77	3.51	3.51
378.41	2.29	2.29
219.20	0.98	0.98
279.30	2.94	2.94
353.77	2.40	2.40
329.74	2.92	2.92
294.31	2.52	2.52
355.78	3.69	3.69
348.36	2.98	2.98
245.28	2.31	2.31
327.32	2.99	2.99
354.39	2.78	2.78
401.85	4.38	4.38
205.17	0.67	0.67
353.35	3.56	3.56
325.32	2.55	2.55
320.31	2.42	2.42
399.83	3.99	3.99
353.35	3.56	3.56
247.25	1.62	1.62
309.32	2.85	2.85
315.72	2.99	2.99
327.31	2.71	2.71
369.81	4.08	4.08
315.72	2.99	2.99
427.77	4.14	4.14
299.26	2.48	2.48
339.35	2.86	2.86
374.19	3.31	3.31
315.72	2.99	2.99
453.86	4.92	4.92
331.28	2.82	2.82
349.35	2.43	2.43
453.86	4.92	4.92
435.22	3.46	3.46
323.35	3.16	3.16
311.30	2.25	2.25
437.40	4.40	4.40
329.74	2.92	2.92
349.35	2.43	2.43
451.22	3.16	3.16
357.80	3.65	3.65
433.41	4.99	4.99
339.33	3.17	3.17
357.80	3.76	3.76
341.34	3.25	3.25
355.78	3.40	3.40
309.27	2.39	2.39
427.77	4.14	4.14
401.85	4.38	4.38
329.74	2.92	2.92
341.34	3.25	3.25
437.40	4.40	4.40
233.23	1.29	1.29
449.89	5.34	5.34
245.24	1.55	1.55
295.30	2.65	2.65
403.82	3.22	3.22
433.44	4.82	4.82
449.87	5.51	5.51
369.81	4.08	4.08
353.77	2.40	2.40
435.43	4.61	4.61