Basic Information
ID: ALA4256953
Type: Binding
Description: Inhibition of recombinant human C-terminal FLAG-tagged FBXL10 (1 to 650 residues) expressed in Escherichia coli using H3K36me2-biotin peptide as substrate after 30 mins in presence of alpha-ketoglutaric acid by AlphaScreen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4256953
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 343.77 | 3.51 | 3.51 |
| 313.29 | 2.68 | 2.68 |
| 399.83 | 3.99 | 3.99 |
| 283.26 | 2.77 | 2.77 |
| 323.35 | 3.11 | 3.11 |
| 435.87 | 4.78 | 4.78 |
| 309.32 | 2.85 | 2.85 |
| 320.31 | 2.42 | 2.42 |
| 295.30 | 2.26 | 2.26 |
| 353.77 | 2.40 | 2.40 |
| 309.32 | 2.82 | 2.82 |
| 327.31 | 2.71 | 2.71 |
| 249.23 | 0.82 | 0.82 |
| 311.30 | 2.25 | 2.25 |
| 315.72 | 2.99 | 2.99 |
| 401.85 | 4.23 | 4.23 |
| 364.19 | 3.57 | 3.57 |
| 331.28 | 2.54 | 2.54 |
| 343.77 | 3.51 | 3.51 |
| 331.28 | 2.54 | 2.54 |
| 273.29 | 2.33 | 2.33 |
| 279.30 | 2.56 | 2.56 |
| 333.36 | 2.30 | 2.30 |
| 335.32 | 2.42 | 2.42 |
| 279.30 | 2.56 | 2.56 |
| 343.77 | 3.51 | 3.51 |
| 219.20 | 0.98 | 0.98 |
| 353.77 | 2.40 | 2.40 |
| 329.74 | 2.92 | 2.92 |
| 354.39 | 2.78 | 2.78 |
| 401.85 | 4.38 | 4.38 |
| 205.17 | 0.67 | 0.67 |
| 399.83 | 3.99 | 3.99 |
| 247.25 | 1.62 | 1.62 |
| 315.72 | 2.99 | 2.99 |
| 327.31 | 2.71 | 2.71 |
| 299.26 | 2.48 | 2.48 |
| 339.35 | 2.86 | 2.86 |
| 315.72 | 2.99 | 2.99 |
| 453.86 | 4.92 | 4.92 |
| 323.35 | 3.16 | 3.16 |
| 437.40 | 4.40 | 4.40 |
| 329.74 | 2.92 | 2.92 |
| 349.35 | 2.43 | 2.43 |
| 357.80 | 3.65 | 3.65 |
| 355.78 | 3.40 | 3.40 |
| 427.77 | 4.14 | 4.14 |
| 329.74 | 2.92 | 2.92 |
| 233.23 | 1.29 | 1.29 |
| 245.24 | 1.55 | 1.55 |
| 295.30 | 2.65 | 2.65 |
| 353.77 | 2.40 | 2.40 |