Basic Information
ID: ALA4256954
Type: Binding
Description: Inhibition of KDM5A/KDM5B in human ZR-75-1 cells assessed as increase in H3K4me3 level after 72 hrs by fluorometric immunoblot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4256954
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 329.74 | 3.20 | 3.20 |
| 343.77 | 3.29 | 3.29 |
| 343.77 | 3.51 | 3.51 |
| 313.29 | 2.68 | 2.68 |
| 295.30 | 2.54 | 2.54 |
| 374.19 | 3.31 | 3.31 |
| 323.35 | 3.11 | 3.11 |
| 309.32 | 2.85 | 2.85 |
| 359.77 | 3.21 | 3.21 |
| 347.73 | 3.34 | 3.34 |
| 313.29 | 2.68 | 2.68 |
| 373.80 | 3.60 | 3.60 |
| 320.31 | 2.42 | 2.42 |
| 327.31 | 2.77 | 2.77 |
| 331.28 | 2.82 | 2.82 |
| 334.34 | 2.72 | 2.72 |
| 345.31 | 2.91 | 2.91 |
| 341.34 | 3.25 | 3.25 |
| 327.31 | 2.99 | 2.99 |
| 347.73 | 3.34 | 3.34 |
| 388.22 | 3.62 | 3.62 |
| 345.31 | 3.13 | 3.13 |
| 334.34 | 2.50 | 2.50 |
| 337.33 | 3.17 | 3.17 |
| 327.31 | 2.99 | 2.99 |
| 329.74 | 3.20 | 3.20 |
| 343.77 | 3.51 | 3.51 |
| 334.34 | 2.72 | 2.72 |
| 347.73 | 3.34 | 3.34 |
| 365.39 | 3.26 | 3.26 |
| 364.19 | 3.85 | 3.85 |
| 357.80 | 3.76 | 3.76 |
| 343.77 | 3.51 | 3.51 |
| 348.36 | 2.98 | 2.98 |
| 327.32 | 2.99 | 2.99 |
| 399.83 | 3.99 | 3.99 |
| 427.77 | 4.14 | 4.14 |
| 339.35 | 2.86 | 2.86 |
| 374.19 | 3.31 | 3.31 |
| 453.86 | 4.92 | 4.92 |
| 331.28 | 2.82 | 2.82 |
| 453.86 | 4.92 | 4.92 |
| 435.22 | 3.46 | 3.46 |
| 323.35 | 3.16 | 3.16 |
| 437.40 | 4.40 | 4.40 |
| 349.35 | 2.43 | 2.43 |
| 451.22 | 3.16 | 3.16 |
| 341.34 | 3.25 | 3.25 |
| 437.40 | 4.40 | 4.40 |
| 449.89 | 5.34 | 5.34 |
| 433.44 | 4.82 | 4.82 |
| 435.43 | 4.61 | 4.61 |