Basic Information
ID: ALA4256958
Type: ADME
Description: Inhibition of human membrane bound C-terminal His4-tagged CYP21A2 delta19H mutant assessed as reduction in progesterone hydroxylation measured after 10 mins in presence of NADPH/NADPH-cytochrome p450 reductase by GC/MS method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4256958
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.52 | 5.40 | 5.40 |
| 307.35 | 2.04 | 2.04 |
| 388.56 | 5.81 | 5.81 |
| 365.52 | 4.66 | 4.66 |
| 374.53 | 5.29 | 5.29 |
| 392.54 | 4.25 | 4.25 |
| 380.53 | 4.92 | 4.92 |