Basic Information
ID: ALA4256961
Type: Binding
Description: Inhibition of c-fms in mouse bone marrow macrophages assessed as reduction in recombinant mouse CSF-1-driven cell proliferation by measuring bromodeoxyuridine incorporation incubated for 30 hrs by ELISA
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4256961
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.58 | 5.87 | 5.87 |
| 447.58 | 4.69 | 4.69 |
| 495.65 | 4.09 | 4.09 |
| 460.63 | 4.61 | 4.61 |
| 474.65 | 5.00 | 5.00 |
| 488.64 | 4.53 | 4.53 |
| 490.65 | 3.97 | 3.97 |
| 504.68 | 4.63 | 4.63 |
| 461.61 | 4.74 | 4.74 |
| 502.66 | 4.57 | 4.57 |
| 509.68 | 4.14 | 4.14 |
| 449.60 | 4.64 | 4.64 |
| 497.67 | 4.04 | 4.04 |
| 504.68 | 4.01 | 4.01 |
| 490.65 | 4.28 | 4.28 |
| 462.60 | 4.09 | 4.09 |
| 364.41 | 3.51 | 3.51 |
| 363.42 | 2.91 | 2.91 |
| 391.48 | 3.55 | 3.55 |
| 455.54 | 2.65 | 2.65 |
| 469.57 | 2.70 | 2.70 |
| 497.62 | 3.33 | 3.33 |
| 475.64 | 5.47 | 5.47 |
| 491.64 | 4.71 | 4.71 |
| 421.55 | 3.94 | 3.94 |
| 435.57 | 4.60 | 4.60 |
| 449.60 | 4.94 | 4.94 |
| 483.64 | 4.00 | 4.00 |
| 497.67 | 4.34 | 4.34 |
| 527.11 | 3.97 | 3.97 |
| 427.53 | 3.28 | 3.28 |
| 391.48 | 3.86 | 3.86 |
| 392.46 | 3.39 | 3.39 |
| 436.52 | 3.02 | 3.02 |
| 420.47 | 2.33 | 2.33 |
| 378.43 | 3.85 | 3.85 |
| 463.65 | 5.41 | 5.41 |
| 479.65 | 4.43 | 4.43 |
| 451.64 | 5.31 | 5.31 |
| 482.61 | 3.00 | 3.00 |
| 427.53 | 2.92 | 2.92 |
| 455.58 | 3.56 | 3.56 |
| 413.50 | 2.58 | 2.58 |
| 441.56 | 3.22 | 3.22 |
| 394.43 | 3.25 | 3.25 |
| 379.42 | 3.15 | 3.15 |
| 514.70 | 7.30 | 7.30 |
| 436.58 | 5.64 | 5.64 |
| 468.61 | 6.18 | 6.18 |
| 532.69 | 4.54 | 4.54 |
| 465.67 | 5.36 | 5.36 |
| 517.67 | 5.24 | 5.24 |
| 477.68 | 5.45 | 5.45 |
| 445.61 | 5.85 | 5.85 |
| 362.39 | 3.59 | 3.59 |
| 408.50 | 3.68 | 3.68 |
| 532.57 | 3.53 | 3.53 |
| 475.47 | 3.72 | 3.72 |
| 472.03 | 4.60 | 4.60 |
| 451.40 | 4.15 | 4.15 |
| 531.54 | 3.84 | 3.84 |
| 519.52 | 3.37 | 3.37 |
| 519.52 | 3.74 | 3.74 |
| 514.07 | 3.44 | 3.44 |
| 512.59 | 4.66 | 4.66 |
| 562.59 | 3.35 | 3.35 |
| 564.52 | 3.70 | 3.70 |
| 458.01 | 3.94 | 3.94 |
| 563.62 | 4.94 | 4.94 |
| 427.94 | 3.32 | 3.32 |
| 436.52 | 2.56 | 2.56 |
| 545.61 | 5.46 | 5.46 |
| 470.02 | 4.00 | 4.00 |
| 576.62 | 3.24 | 3.24 |