Basic Information
ID: ALA4256998
Type: Binding
Description: Inhibition of recombinant human C-terminal FLAG-tagged FBXL10 (1 to 650 residues) expressed in baculovirus infected Sf9 cells using H3K36me2-biotin labelled peptide as substrate measured after 1 hr by AlphaScreen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4256998
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 428.42 | 4.39 | 4.39 |
| 415.43 | 3.73 | 3.73 |
| 408.41 | 4.00 | 4.00 |
| 454.46 | 4.88 | 4.88 |
| 400.36 | 3.81 | 3.81 |
| 454.46 | 4.88 | 4.88 |
| 388.33 | 3.94 | 3.94 |
| 384.37 | 4.11 | 4.11 |
| 391.44 | 4.00 | 4.00 |
| 384.37 | 4.36 | 4.36 |
| 414.39 | 4.00 | 4.00 |
| 452.36 | 5.01 | 5.01 |
| 296.72 | 2.86 | 2.86 |
| 468.36 | 4.74 | 4.74 |
| 414.39 | 3.91 | 3.91 |
| 381.44 | 3.72 | 3.72 |
| 370.34 | 3.80 | 3.80 |
| 418.81 | 4.65 | 4.65 |
| 420.35 | 4.27 | 4.27 |
| 346.39 | 2.98 | 2.98 |
| 296.72 | 2.86 | 2.86 |
| 310.75 | 2.92 | 2.92 |
| 402.36 | 4.24 | 4.24 |
| 402.36 | 4.13 | 4.13 |
| 390.42 | 3.86 | 3.86 |
| 420.35 | 4.27 | 4.27 |
| 356.43 | 3.85 | 3.85 |
| 345.19 | 3.57 | 3.57 |
| 226.24 | 1.27 | 1.27 |
| 440.47 | 5.29 | 5.29 |
| 310.75 | 2.92 | 2.92 |
| 320.33 | 3.07 | 3.07 |
| 350.36 | 3.08 | 3.08 |
| 388.33 | 4.09 | 4.09 |
| 366.43 | 4.13 | 4.13 |
| 354.78 | 3.57 | 3.57 |
| 426.40 | 4.32 | 4.32 |
| 240.27 | 1.63 | 1.63 |
| 414.37 | 4.42 | 4.42 |
| 296.72 | 2.86 | 2.86 |
| 350.36 | 2.93 | 2.93 |
| 384.37 | 3.99 | 3.99 |
| 316.37 | 3.34 | 3.34 |
| 350.81 | 3.63 | 3.63 |
| 467.46 | 4.23 | 4.23 |
| 452.36 | 5.01 | 5.01 |
| 294.29 | 2.56 | 2.56 |
| 442.42 | 5.01 | 5.01 |
| 384.42 | 4.27 | 4.27 |
| 276.30 | 2.26 | 2.26 |
| 442.42 | 5.01 | 5.01 |
| 388.33 | 3.94 | 3.94 |
| 412.42 | 4.55 | 4.55 |
| 404.78 | 4.45 | 4.45 |
| 378.87 | 4.36 | 4.36 |
| 404.78 | 4.45 | 4.45 |
| 268.20 | 1.78 | 1.78 |
| 442.42 | 5.01 | 5.01 |
| 364.38 | 3.47 | 3.47 |
| 438.33 | 4.41 | 4.41 |
| 384.37 | 4.11 | 4.11 |
| 371.23 | 4.09 | 4.09 |
| 375.82 | 3.50 | 3.50 |
| 389.22 | 4.22 | 4.22 |
| 404.33 | 3.82 | 3.82 |
| 410.40 | 4.48 | 4.48 |
| 436.80 | 4.78 | 4.78 |
| 400.87 | 4.78 | 4.78 |
| 364.38 | 3.35 | 3.35 |
| 404.78 | 4.45 | 4.45 |
| 415.68 | 4.19 | 4.19 |
| 438.46 | 5.18 | 5.18 |
| 330.40 | 3.53 | 3.53 |
| 402.36 | 4.13 | 4.13 |
| 418.81 | 4.65 | 4.65 |
| 402.36 | 4.24 | 4.24 |
| 410.27 | 4.15 | 4.15 |
| 438.46 | 5.18 | 5.18 |
| 406.32 | 4.08 | 4.08 |
| 400.36 | 3.87 | 3.87 |
| 392.47 | 4.64 | 4.64 |
| 454.46 | 4.88 | 4.88 |
| 497.13 | 4.69 | 4.69 |
| 420.35 | 4.27 | 4.27 |
| 386.46 | 3.76 | 3.76 |
| 310.75 | 2.92 | 2.92 |
| 406.32 | 4.08 | 4.08 |
| 408.47 | 4.77 | 4.77 |
| 412.42 | 4.99 | 4.99 |
| 398.39 | 4.30 | 4.30 |
| 334.36 | 3.23 | 3.23 |
| 438.33 | 4.41 | 4.41 |
| 402.36 | 4.13 | 4.13 |
| 492.32 | 4.73 | 4.73 |
| 358.41 | 3.30 | 3.30 |
| 422.49 | 4.55 | 4.55 |
| 398.39 | 4.75 | 4.75 |
| 467.46 | 4.23 | 4.23 |
| 360.42 | 3.37 | 3.37 |
| 331.17 | 3.51 | 3.51 |
| 424.43 | 4.87 | 4.87 |
| 454.46 | 4.88 | 4.88 |
| 420.35 | 4.27 | 4.27 |
| 434.43 | 5.14 | 5.14 |
| 424.87 | 4.52 | 4.52 |
| 336.79 | 3.43 | 3.43 |